ethiopia small high pressure micro powder mill

stone crushers, sand makers, grinding mills manufacturer in china - fote machinery

How to choose a right ball milling method for your material?1.Definition of wet milling method and dry milling method.2.It is the key to choose the right ball milling method.3.Precautions in the process of selecting a grinding method.4.Wet ball mill is more economical and practical than dry ball mill.

Advantages of wet magnetic separator in coal preparation.1.Importance of processing the coal mine correctly.Necessary equipment for coal preparation---wet counter-current magnetic separator.Wet counter-current magnetic separator has great graces in the coal preparation process.

joyal-high pressure grinding mill,high pressure grinding mill for sales,high pressure grinding mill manufacturer

JOYAL High Pressure Mill is an improved type of Raymond mill. The purpose of the this kind mill is to grind non-flammable and non-explosive materials in the fields of building materials, mining, metallurgies and chemical industry with hardness less than 9.3 in Mohs scale and humidity less than 6 percent.

General:Crushing -- Grinding -- Selecting -- Collecting Detailed:The High-pressure Suspension Mill has the same working principle as Raymond Mill, but its grinding fitting is furnished with 1000 - 1500 kg pressure spring. When the machine works, the grinding roll, under the action of high pressure spring and centrifugal force, rolls close up to grinding ring, its rolling pressure ratio is 1.2 times of Raymond mill given an identical condition, and its output may increase 10% to 20%Please note that when the grinding roller and grinding ring reach a certain degree of abrasion, please adjust the length of high-pressure spring to keep the constant grinding pressure between grinding roller and grinding ring, so as to ensure a stable output and fineness.

laboratory spray dryer,ultrasonic cell disruptor,life science instrument

Lab spray dryer capacity has 2L/H, 3L/H, 5L/H, 10L/H,15L/H, which could dry solution and emulsion to powder or granule products directly, don't need evaporation and crushing process. Customization of spray dryer is available.

PCB engraving machine manufacturer, focusing on the precision R&D board-making needs of high-end enterprises and school customers at home and abroad, providing circuit board engraving machines and related equipment for drilling, engraving, and shape milling of copper clad laminates.

High pressure autoclaves for chemical reactions like hydrogenation, oxidation, alkylation, chlorination. carboxylation, nitration, polymerization, amination, bromination,ethoxylation, esterification, sulphonation etc.

Our main products include: lab single screw extruder, lab twin screw extruder, lab banbury mixer, lab sheet extrusion line,lab cast film machine, lab blown film machine, lab three-roll calender, lab two roll Mill, 3D printer filament extruder.

Our main products include: lab single screw extruder, lab twin screw extruder, lab banbury mixer, lab sheet extrusion line,lab cast film machine, lab blown film machine, lab three-roll calender, lab two roll Mill, 3D printer filament extruder.

The machine is used to mix the raw material and additional agents uniformly for testing, and apply the experiment results and its ratio in the production line to satisfy the requirements of quality and color which specified by the customer.

User can select the number of small lab extruder according to the structure of the film, and combine with the double layer cast film die, three layer cast film die or five layer cast film die to form a small lab multi-layer co-extruded cast film machine.

The working principle is: the material flow is put in the hopper and passed through the extrusion device to be plasticized and extruded into a casting state, and then comes out of the host through the die, and is calendered by a two-roll calender.

PCB engraving machine manufacturer, focusing on the precision R&D board-making needs of high-end enterprises and school customers at home and abroad, providing circuit board engraving machines and related equipment for drilling, engraving, and shape milling of copper clad laminates.

The dry ice pelletizer can produce dia 3mm to dia 19mm of high strength, particle or columnar, with its production capacity is from 50kg/h to more than 1000kg/h. The dry ice cube making machine can commonly produce ice block in thickness from 10mm to 210mm,. Both of these 2 types machines can be customized according to customer's requirement.

The core thermal insulation material of the dry ice incubator: polyurethane rigid foam. Our company has obtained technical guidance and support from the Aerospace Group on the formulation of this material.

Ice cleaning is applied to the tire industry, rubber casting, automotive, aerospace, machinery manufacturing, mold industry, printing equipment, oil and chemical industry, breaking the traditional time-consuming wash, cut and other shortcomings, efficient, energy-saving and clean, environmentally friendly online new cleaning mode.

Main products line: CBD extraction line, laboratory pharmaceutical production line. Main equipment:Spray dryer,Molecular distillation,High pressure reactor,Crushing equipment, drying equipment.

overview of milling techniques for improving the solubility of poorly water-soluble drugs - sciencedirect

Milling involves the application of mechanical energy to physically break down coarse particles to finer ones and is regarded as a topdown approach in the production of fine particles. Fine drug particulates are especially desired in formulations designed for parenteral, respiratory and transdermal use. Most drugs after crystallization may have to be comminuted and this physical transformation is required to various extents, often to enhance processability or solubility especially for drugs with limited aqueous solubility. The mechanisms by which milling enhances drug dissolution and solubility include alterations in the size, specific surface area and shape of the drug particles as well as milling-induced amorphization and/or structural disordering of the drug crystal (mechanochemical activation). Technology advancements in milling now enable the production of drug micro- and nano-particles on a commercial scale with relative ease. This review will provide a background on milling followed by the introduction of common milling techniques employed for the micronization and nanonization of drugs. Salient information contained in the cited examples are further extracted and summarized for ease of reference by researchers keen on employing these techniques for drug solubility and bioavailability enhancement.

small precision tools - ceramic injection molding

SPTs wire bonding capillaries utilize a state-of-the-art Ceramic Injection Molding (CIM) technology to achieve reproducibility from the first piece up to the nth piece with excellent consistency to meet customers tighter dimensional tolerance and robust bonding performance requirement in a cost effective way.

Block diagram of state-of-the art- ceramic injection molding (CIM) for capillary The Process Small Precision Tools injection molding process is a combination of powder, injection molding, and sintering technologies. To obtain the necessary chemical and physical properties, powders are selected by size and shape and complemented with additives. Every particle of the powder is coated with binder components, which transport the powder for molding and gives the final form rigidity. The ceramic injection molding is very suitable for high volume production of complex design with tight tolerances like bonding capillaries. It is an effective way of manufacturing complex precision components with the highest degree of repeatability and reproducibility. Process flow for capillary manufacturing process Stage 1 The characteristics of the ceramic powders, such as grain size distribution and morphology play a vital role not only in the achievement of the desired product properties, but also in the success of the different stages of the process. The ceramic powders used for the manufacturing of capillaries are selected by size and shape and complemented with additives to obtain the necessary chemical and physical properties. Stage 2 - 3 Before the injection molding, the powder is mixed with binder to form a homogeneous mixture that is used to form the shape of the capillary. The binder is used for the artificial plasticisation of the ceramic powders and for the formation of the desired shape through injection molding. Consideration for binder selection includes the flow characteristics for injection molding, the ease of binder removal and binder-powder interaction. Stage 4 - 5 Subsequently, the mixture is feed to the mold for injection molding. The molding process is a significantly affected by the temperature, pressure and time envelope and it is essential to have the correct temperature and pressure sequence together with the time sequence. Stage 6 The binder is removed by evaporation and exothermic reaction, leaving only a small fraction behind. Removal of the binder is a critical step between the molding operation and the sintering process. The extent of the binder removal requires careful monitoring and control to retain the shape of the capillary. Stage 7 The formed part is then sintered in an oxidizing or reducing atmosphere, or in a high vacuum at temperature of up to 1800C. During sintering, the parts become more dense and shrink. Depending on the raw material properties, shrinkage ranges from 15% to 25% of its molded dimensions. Repeatably attaining the required dimensional tolerances on the sintered parts requires that the green density of the part be uniform within each part and consistent from part to part, and that the shrinkage during sintering be repeatable and predictable.

The Advantages: Small Precision Tools injection molding process offers a high degree of reproducibility. Complex parts in ceramic can be shaped in one operation with diverse geometry, different profiles, undercuts, sharp edges, and different wall thickness.

The Application Horizon: Today, the Small Precision Tools injection molding process is applied in the instrumentation, textile, automobile, printing, electronic assembly, communications, aerospace, optical, medical, dental and chemical industries. Cost effective applications are found in relatively small parts demanding complex machining operations, and where volume production requires a large investment in machine tools Market: Medical, Dental, Industrial, Mechanical

inline mixer | high shear in-line mixers

Silverson High Shear In-Line mixers are supremely efficient and rapid in operation and are capable of reducing mixing times by up to 90%. The action of any Silverson In-Line mixer can be modified with the use of rapidly interchangeable workheads. This enables any machine to mix, emulsify, homogenize, solubilize, suspend, disperse and disintegrate solids.

Silversons line of high shear In-Line mixers offers a great many advantages to the processor - speed, versatility, self-pumping, aeration-free, guaranteed efficiency. At the heart of every mixer is Silversons high performance rotor/stator workhead.

Centrifugal force then drives the materials towards the periphery of the workhead where they are subjected to a milling action in the precision-machined clearance between the ends of the rotor blades and the inner wall of the stator.

This is followed by intense hydraulic shear as the materials are forced, at high velocity, out through the perforations in the stator, then through the machine outlet and along the pipework. At the same time, fresh materials are continually drawn into the workhead, maintaining the mixing and pumping cycle.

Centrifugal force then drives the materials towards the periphery of the workhead where they are subjected to a milling action in the precision-machined clearance between the ends of the rotor blades and the inner wall of the stator.

This is followed by intense hydraulic shear as the materials are forced, at high velocity, out through the perforations in the stator, then through the machine outlet and along the pipework. At the same time, fresh materials are continually drawn into the workhead, maintaining the mixing and pumping cycle.

A comprehensive range of workheads and screens is available for all Silverson high shear mixers. These easily interchangeable workheads offer great versatility by allowing any machine to be adapted to perform a wide range of mixing operations including emulsifying, homogenizing, disintegrating, dissolving, dispersing, blending, particle size reduction and de-agglomerating. Changing from one head or screen to another is quick and simple.

Used for a wide range of applications, this head will give the greatest throughput. Suitable for the blending of liquids of similar or greatly varying viscosities, its uses include the disintegration of solid and semi-solid materials.

Used for a wide range of applications, this head will give the greatest throughput. Suitable for the blending of liquids of similar or greatly varying viscosities, its uses include the disintegration of solid and semi-solid materials.

The configuration and fine internal tolerances of this stator provide exceptionally high shear rates which are ideal for the rapid size reduction of soluble and insoluble granular solids. It is also suitable for the preparation of emulsions, gels and thickeners and fine collodial suspensions.

The configuration and fine internal tolerances of this stator provide exceptionally high shear rates which are ideal for the rapid size reduction of soluble and insoluble granular solids. It is also suitable for the preparation of emulsions, gels and thickeners and fine collodial suspensions.

Silverson offers a range of In-Line mixers suitable for hazardous and aggressive chemical service. These robust mixers require minimal maintenance and provide some of the highest rotor tip speeds and shear rates in the industry. Self-pumping capacities from 5 to 50,000 gallons per hour.

The Multistage In-Line Mixer quadruples a number of shearing actions per revolution of the rotor, resulting in substantially faster mixing times and also increasing the number of products that can be processed in a single pass.

Silverson offers a range of In-Line mixers suitable for hazardous and aggressive chemical service. These robust mixers require minimal maintenance and provide some of the highest rotor tip speeds and shear rates in the industry. Self-pumping capacities from 5 to 50,000 gallons per hour.

The Multistage In-Line Mixer quadruples a number of shearing actions per revolution of the rotor, resulting in substantially faster mixing times and also increasing the number of products that can be processed in a single pass.

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Ethiopian Airlines Group, the largest Pan-African airline, has become Africas top airline in passenger and freight traffic retaining its leadership position in the continent. According to the African Airlines Associations...

Prime Minister Abiy Ahmed, along with Addis Ababa city Deputy Mayor Adanech Abiebie and other senior government officials, has inaugurated the grand Meskel Square-Addis Ababa City Hall project. Part of...

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joyal-three-ring micro powder mill,three-ring micro powder mill for sales,three-ring micro powder mill manufacturer

The JOYAL Three-ring Micro Powder Mill(ultrafine mill) is for super-fine grinding materials with hardness less than 6 in Mohs scale and humidity less than 6 percent such as kaolin, limestone, calcite, marble,talcum, barite, gypsum, dolomite, bentonite mud,mica, pyrophyllite, sepiolite, diatomite, graphite, alunite, fluorite, potassium feldspar, phosphorite, pigment and so on. The granularity of the end products is 325-2500 meshes (0.044-0.0055mm).

General:Crushing -- Grinding -- Selecting -- Collecting Detailed:The main bearing and each dial are driven by electromotor of main equipment through reducer, and numbers of rings and rolls which are rolling in the ring channels are driven by dial through plunger. After being crushed by hammer crusher, the big materials become small ones and they are sent to the storage bin by elevator. The electromagnetic vibrating feeder sends them to the middle of first dial evenly; the materials will be driven to the edge of dial by centrifugal force, and fall into the ring channels and are pressed, crushed and ground by the grinding rings and rolls. Then the materials fall into the second and third ring and crushed and ground. The high pressure centrifugal blower inhales air from the outside and blow the materials which are ground in the third ring to powder Separator. The rotating turbo in the powder Separator makes the coarse materials return to the mill and reground, while the fineness mixes with the air and be drawn to the cyclone and be discharged from the discharging valve which is in the bottom of it. The air which mixed with very little fineness are purified by impulse dust catcher and discharged by blower and muffler.

compression issues: causes and remedies

Usually, when evaluating a new tablet press, one of the first questions asked concerns the number of compression stations. The number of tablets that can be produced with a press is a crucial parameter for every manufacturer of solid dosage forms. And, for single rotary tablet presses, this is a number that can easily be calculated by multiplying the number of stations by the rotation speed and the running time in minutes. For example, a press with 25 stations running with 120 revolutions per minute produces 180,000 tablets per hour.

In an actual pharmaceutical manufacturing environment, however, the number of stations plays a somewhat less important role regarding the number of tablets that can be produced with a particular press. The majority of pharmaceutical tablets are not produced at the presss maximum compression speed because it is not possible to produce tablets of acceptable quality at high rotation speeds. Defects such as capping, sticking and lamination occur, and the tablets become subject to weight and content variations. In many cases, reducing the rotation speed of the press makes it possible to avoid these problems. As such, the simple relationship between reduced rotation speed and fewer out-of-specification tablets will be observed.

Usually, eccentric presses or small, rotary tablet presses operated at slow speeds are used when developing tablets. Often, the development process focuses on optimizing tablet characteristics such as hardness, disintegration time, stability and/or friability. Less attention is paid to the tableting process itself, as very different operating parameters will be used during full-scale production. Typically, tableting problems only occur during scale-up and when using high-speed production-scale machines. This phenomenon will be explained below using tablet capping as an example.

The extent to which a tablet is prone to capping depends on the deformation behaviour of individual components. If materials are used that deform plastically or undergo brittle fracture, the risk is low. But, if the tablet formulation contains substances that deform elastically or demonstrate viscoelastic deformation, there is a high risk of capping, particularly with rapidly applied loads. The situation is exacerbated if the active pharmaceutical ingredient (API) itself shows this behaviour and has to be incorporated into the tablet in high concentrations. In almost all other cases, capping can be avoided completely by the appropriate choice of pharmaceutical excipients. However, capping will always occur if, following compression, more elastic energy is accumulated in the tablet than its inner structure can absorb.

Apart form the choice of excipients, the processes that precede tableting also influence the tablets tendency to cap. In the case of direct compression, only the compression properties of the substances used will define the extent of the capping potential. Another problem associated with direct compression is the higher proportion of fines, which also increase the tendency to cap. Wet granulation, by contrast, enables capping to be minimized, according to how evenly the binder is distributed during granulation. Therefore, granulates that have been produced by spray granulation generally cap less than those produced using an intensive mixer granulator.

Another cause of capping is entrapped air that has been compressed during main compression and eventually shatters the tablet as a result of perfect elastic behaviour. The more open-pored a material is usually discernible by its low bulk density the more air it contains. The majority of this air should be removed during pre-compression. Yet, the problem here is that with faster tableting speeds, less time is available. Different tablet press manufacturers have developed a variety of concepts to improve this situation; as such, the speed of the press can be increased by up to four times for critical formulations [1].

If the diameter of the tablet press rotor is Xcm, then the die covers a distance of S = X * cm during one rotation. The circumferential speed (V), measured in m/s, can be calculated as follows: V = S * rpm/60 (with rpm being the number of rotations per minute). The division by 60 is necessary to define the speed in m/s.

If a press is operated at a lower rotation speed to avoid problems with capping, this can be equated to a reduction of the circumferential speed. In other words, capping can be prevented if the press runs below a certain circumferential speed. Thus, if a formulation has a strong tendency to cap, the number of tablets produced per hour cannot be improved by simply increasing the number of pressing stations. Only a reduction in the distance between the dies, which is offered by several manufacturers, can improve the output (Table I) [2,3].

Press A is the reference. Press B is identical, but has a bigger rotor. Press C has the same rotor as press B, but the number of press stations has been increased by reducing the distance between the single dies [2,3]. Assuming that the maximum circumferential speed is 2.5 m/s owing to capping, this results in the fact that the larger presses (B and C) have to operate at a reduced rotation speed compared with Press A. As a result of linear correlation, in the case of press B, this counteracts the effect of the increased number of pressing stations. The higher output achieved with Press C is the result of the reduced distance between the single dies.

Usually, it is not possible to change the formulation during scale-up from R&D to production to reduce the tendency to cap. And, in most cases, only minor adjustments can be made to optimize upstream processes. Apart from reducing the number of turret rotations, and therefore the circumferential speed, only two other options remain. On one hand, punches with larger heads can be used. And, on the other hand, it is possible to retract the upper punch more slowly following main compression. As a result, in many cases, the stored energy can be transferred to the upper punch without the tablets being destroyed by capping.

Each tableting process aims to produce tablets with a constant weight. Yet, as a result of variations in the density of the feed material and partial or incomplete filling of the dies, there are always weight variations (the relevant pharmacopoeia specify acceptable weight variation levels). The threat of weight variation is minimized if the feed material is produced by granulating or compaction; ideally, the composition of the feed material should be determined down to single particle characteristics. But, if the feed material has a wide particle size and/or density distribution, the risk of segregation and subsequent weight and tablet content variation is high. This danger can be minimized by mechanically decoupling the press and the feed material to minimize the risk of segregation. Furthermore, allowing the feed material to free fall between unit operations should be avoided.

Similar to capping, content variations are more pronounced at higher press speeds: with increasing rotation rates, the ruling speed also increases, which means that the period that the die remains under the filling unit decreases. This means that with increasing press speeds, greater demands must be made on the flowability of the feed material. An alternative approach would be to impose a maximum circumferential speed for each powder flowability rate to guarantee uniform die filling.

There are different ways to characterize flowability, including the Hausner factor or by determining the angle of repose, and one of the key tasks of developing mainstream processes must be to significantly improve the flowability of the feed material. A detailed consideration would go beyond the scope of this article; but, generally, every effort should be made to granulate the material with the greatest possible mechanical energy while minimizing the formation of lumps and caking. This material must be milled again during downstream processing, which results in an increased amount of fines and poor flowability.

During scale-up from R&D to production, upstream processes can only normally be optimized within very narrow limits. But, often, the situation can be improved by using a forced filling approach. If the lower punch is retracted before the die reaches the filling unit area, the material enters the die as a result of gravity. With forced filling, however, the lower punch is flush with the die table. The lower punch is then pulled into its target position below the filling unit. The material is sucked into the die because of the resulting vacuum, which makes it possible to use high pressing speeds even if the material doesnt flow optimally.

The number of tablets that can be produced with a tablet press per time unit depends only partly on the number of existing pressing stations. In most cases, the operating speed of the press has a much greater influence. This speed depends on the design of the press and particularly on the characteristics of the feed material. The quality of the feed material is strongly determined by its composition and the upstream processes used to prepare it for tableting.

The number of tablets that can be produced with a press is a crucial parameter for every manufacturer of solid dosage forms. And, for single rotary tablet presses, this is a number that can easily be calculated by multiplying the number of stations by the rotation speed and the running time in minutes. For example, a press with 25 stations running with 120 revolutions per minute produces 180,000 tablets per hour.

GEA is one of the worlds largest systems suppliers for the food, beverage and pharmaceutical sectors. The international industrial technology group specializes in machinery and plants as well as advanced process technology, components and comprehensive services. With more than 18,000 employees, the group generated revenue of more than EUR 4.6 billion in fiscal year 2020. A major focus is on continuously enhancing the sustainability and efficiency of customers production processes. GEA plants, processes and components help achieve significant reductions in carbon emissions, plastic use and food waste in production worldwide. In this way, GEA makes a decisive contribution toward a sustainable future, fully in line with its corporate philosophy of engineering for a better world.