high frequency screen 4 test

high frequency carrier screen (11 genes) - sema4

The high frequency pan-ethnic panel provides carrier screening for the following genetic disorders due to the relatively elevated carrier frequencies and high detection rates in most ethnic groups with severe, early onset clinical presentation: Alpha-thalassemia, beta-thalassemia, beta-globin-related hemoglobinopathies: HbC variant, sickle cell disease, congenital disorder of glycosylation: type Ia, cystic fibrosis, Duchenne muscular dystrophy/Becker muscular dystrophy, fragile x syndrome, medium chain acyl-CoA dehydrogenase deficiency, phenylalanine hydroxylase deficiency, Smith-Lemli-Opitz syndrome, and spinal muscular atrophy.

Although this testing can detect the majority of disease-causing pathogenic variants, a negative result does not eliminate the possibility that an individual is a carrier of a rare pathogenic variant that was not identified. Please refer to the residual risk table to determine the risk following a negative result.

standard carrier screening (4 genes) - sema4

CF is an autosomal recessive disease caused by pathogenic variants in the CFTR gene. It can result in the production of unusually thick mucus, which primarily affects breathing, digestion, and reproduction. CF is a chronic and progressive disease, for which there is no cure. This carrier screen is performed by sequencing and targeted genotyping analyses.

Fragile X syndrome is the most common inherited form of mental retardation. It is caused by a change in the FMR1 gene on the X chromosome, so is inherited in an X-linked manner. Within the FMR1 gene, there is a region of repeating DNA bases referred to by the letters CGG. The number of CGG repeats present within the FMR1 gene determines if an individual has fragile X syndrome or is at risk to have a child with fragile X syndrome.

SLOS is a disorder involving cholesterol metabolism. Some features of SLOS include growth retardation, microcephaly (small head circumference), moderate-to-severe intellectual disability, behavior problems, and physical malformations like distinctive facial features, cleft palate, cardiac defects, underdeveloped external genitalia in males, and finger/toe abnormalities. The gene associated with SLOS is DHCR7. Like CF, this carrier screen is performed by sequencing and targeted genotyping analyses.

SMA is a disease that results in severe and progressive weakness of the voluntary muscles affecting breathing, swallowing, head and neck control, crawling, and walking. SMA is an autosomal recessive condition caused by a deletion and/or pathogenic variant in both copies of the SMN1 gene. Carrier testing for SMA is performed in two ways. First, genetic testing to determine the number of SMN1 gene copies present in an individual is carried out. This method can detect ~90-94% of SMA carriers. The second method of testing is by analysis for a genetic marker (g.27134T>G) that is oftentimes found on chromosomes that have 2 copies of SMN1 gene copies, which modifies the residual risk of being a silent carrier.

Although this testing can detect the majority of disease-causing pathogenic variants, a negative result does not eliminate the possibility that an individual is a carrier of a rare pathogenic variant that was not identified. Please refer to the residual risk table to determine the risk following a negative result.

how to interpret an audiogram from a hearing test

An audiogram is set up as a chart with the horizontal X-axis representing frequencies, or Hertz (Hz). The X-axis is divided into two parts: On the left side of the "divide" are the low frequencies. On the right side of the "divide" are the high frequencies.

The vertical Y-axis represents decibels. Decibels represent the hearing level, or how loud it is. The number of decibels are lower at the top of the chart, and get higher as you go downward. It is divided into three parts: The top part of the chart is the softer sounds, the middle part is the moderate sounds, and the bottom part is the louder sounds.

The audiologist tests your hearing at a range of frequencies. The audiologist is checking to see what the softest sound you can hear at each frequency is. For example, at 125 Hz you may be able to only hear the sound at 50 decibels.

online tone generator - generate free low frequency tones to test your subwoofer

This page contains a low frequency sweep and a series of tones for testing the response of subwoofers. Click the play button below to begin the test. You will hear a sine wave start at 150Hz and gradually decrease to 1Hz over the course of 60 seconds. We have also provided a series of continuous tones (compatible with Firefox 4 or later) to help you get the most out of your subwoofers. How well do your subs perform? Let us know in the comments section at the bottom of the page.

high frequency test sieve shaker sieve analysis machine 3000 times/min

High Frequency Test Sieve Shaker Sieve Analysis Machine 3000 Times/Min Overview of High Frequency Three Dimensional Electromagnetic Vibration Test Sieve Shaker: Our AT-200 High Frequency Three Dimensional Electromagnetic Vibration Test Sieve Shakercan be used for both dry and wet screening. This sieve shakerdoes three dimensional vibration. Itis the best equipment for laboratory particle size inspection and screening on site. The AT-200 test sieve shaker is one of our main products. It is only designed and made by our factory at the moment in China. Compared with the same kind of electromagnetic test sieve shaker on the Chinese market, our AT-200 price is a little higher. But the test effect and result are much better than the traditional electromagnetic vibration test sieve shaker. Besides, the body shell adopts stainless steel wire drawing technology, simple and beautiful. So you will get what you pay. This device can be widely used in pharmaceutical, metallurgy, food, super hard materials and other industries for particle analysis. It is a simple, efficient and precise screening tool that can reproduce the results of analysis very well. Technical Parameters of High Frequency Three Dimensional Electromagnetic Vibration Test Sieve Shaker: NO. Name Unit Data 1 Sieve Number pcs 18 2 Screen Diameter mm 200 100 75 3 Particle Size mm 0.0283 4 Noise dB 50 5 Amplitude mm 03 6 Vibration Frequency times/min 3000 7 Operating Mode Kind 9 8 Power Supply V;Hz 220; 50 9 Power KW 0.2 10 Weight Kg 30 Feeding Material for High Frequency Three Dimensional Electromagnetic Vibration Test Sieve Shaker: 1. Max Screening Capacity: 2.5 Kg 2. Max Sieve Tower Weight: 3.2 Kg 3. Max Loading Weight: 5.8 Kg (sample materials + analysis sieves) 4. Max Sieve Tower Height: 460 mm Features of High Frequency Three Dimensional Electromagnetic Vibration Test Sieve Shaker: 1. With advanced numerical control circuit, the operating parameters such as amplitude, frequency and control time can be accurately adjusted. 2. Low noise, light weight, no need to fix and easy to operate. 3. Suitable for dry screening and wet screening. 4. AT-200 electromagnetic vibration test sieve shaker adopts advanced powerful electromagnetic vibrator to produce optimized three-dimensional vibration, which makes the sieved samples not only vibrate vertically, but also roll over, so that it can make full use of the screen area to achieve the best result that can be reproduced. It also can be used in Wet Screening by equipping with the inlet and outlet nozzle. When ordering our AT-200 test sieve shaker, please let me know the voltage, hertz, sieve number, mesh size for each sieve. If you have special requirement for the motor brand, please also tell us in advance. Item Required Requirement Motor Brand if special required Voltage (Single Phase) 220V, 110V, or other? Hertz 50HZ, or 60HZ ? Sieve Number 1~8 available Mesh Size for each sieve

Our AT-200 High Frequency Three Dimensional Electromagnetic Vibration Test Sieve Shakercan be used for both dry and wet screening. This sieve shakerdoes three dimensional vibration. Itis the best equipment for laboratory particle size inspection and screening on site.

The AT-200 test sieve shaker is one of our main products. It is only designed and made by our factory at the moment in China. Compared with the same kind of electromagnetic test sieve shaker on the Chinese market, our AT-200 price is a little higher. But the test effect and result are much better than the traditional electromagnetic vibration test sieve shaker. Besides, the body shell adopts stainless steel wire drawing technology, simple and beautiful. So you will get what you pay.

This device can be widely used in pharmaceutical, metallurgy, food, super hard materials and other industries for particle analysis. It is a simple, efficient and precise screening tool that can reproduce the results of analysis very well.

4. AT-200 electromagnetic vibration test sieve shaker adopts advanced powerful electromagnetic vibrator to produce optimized three-dimensional vibration, which makes the sieved samples not only vibrate vertically, but also roll over, so that it can make full use of the screen area to achieve the best result that can be reproduced.

high-frequency hearing loss: what is it and how is it treated?

One of the most common types of hearing loss is known as high-frequency hearing loss. This means high-pitched sounds are harder to hear. It can affect anyone of any age, but is common in older adults with age-related hearing loss, as well as people exposed to loud noises.

When listening to people speak,you may struggle to hear certainconsonants(such as s, h or f), whichare spoken at a higher pitch. As a result, speech may sound muffled, especially when you're using the telephone, watching television,or in noisy situations. People with this type of hearing loss often say they feel like they can hear, but not understand.

Diagnosis ofhigh-frequency hearing loss is made aftera hearing test in a sound-treated booth at a hearing clinic. A hearing instrument specialist or audiologist usually will conduct the test. The results are plotted onanaudiogram. If a person has high-frequencyhearing loss, the audiogram will showa slope to the right, indicating a person has trouble hearing frequencies between 2,000 and 8,000 Hz.

A person may have mild, moderate, moderately severe, severe or profound hearing loss. (See degrees of hearing loss to learn hearing loss severity is measured.) In the example below, the person has moderately severe high-frequency hearing loss that is slightly worse in the right ear.

High-frequency hearing loss occurs when the tiny hair-like sensory hearing cells in your cochlea (inner ear) are damaged. These hair cells, known as stereocilia,are responsible for translating the sounds your ears collect into electrical impulses, which your brain eventually interprets as recognizable sound.

Age-related hearing lossis called presbycusis. Because this is a slow process thatusually affects both ears equally, its often difficult to notice. One of the first signs is difficultyunderstanding speech in noisy environments.

Millions of Americans have hearing damage due to noise-induced hearing loss. The damage can occur as the result of a one-time, loud exposure to noise, such as a gunshot or explosion, or can occur over time with constant exposure to noise louder than 85 decibels.

Some types of drugs are ototoxic, meaning they are harmful to your hearing health. Some of the more common ototoxic drugs include salicylates (aspirin) in large quantities, drugs used in chemotherapy treatments and aminoglycoside antibiotics.

Menieres disease, which affects the inner ear, often occurs between the ages of 30-50 and may include fluctuating hearing loss, tinnitus and vertigo or intense dizziness. In severe cases, though,it typically causes low-frequency hearing loss.

Typically, thebest type of hearing aidfor high-frequency hearing loss is whats known as a receiver in the ear (RITE) with adome that sits in the ear canal. This style has an open fit so it doesn't muffle the low-frequency sounds that youstill hear naturally.It can be programmed to amplify only the frequencies you struggle to hear.

While some people want to wear devices that are invisible (known as invisible-in-the-canal or completely in the canalhearing aids), they often dont work well for this type of hearing loss, because they block low-frequency sounds.

It's important to address high-frequency hearing loss as its effects extend far beyond struggling to hear. When children have high-frequency hearing loss, it can impede speech and language development, affecting their ability to excel in school. In older adults, untreated hearing loss is associated with a higher risk of cognitive decline, social isolation, depression and injury-causing falls.

High-frequency hearing loss isnt reversible, but in some cases, it is preventable. One of the best prevention techniques is to protect your hearing against exposure to noiseespecially noise louder than 85 decibels. Keep the volume turned down on your personal electronic devices and wear hearing protection whenever you anticipate being in a noisy environment, such as at the shooting range, when riding snowmobiles, or when attending a live concert or sporting event.

Inexpensive ear plugs are available at the local drugstore for occasional use. If you regularly engage in very noisy hobbies, consider investing in specialized hearing protection such as noise-cancelling headphones or custom-made earmolds, which can be purchased through many hearing healthcare professionals.

If you suspect you have hearing loss, use our online directory of consumer-reviewed hearing clinics to find hearing aid centers near you and make an appointment to get your hearing tested. Research indicates most hearing aid wearers are satisfied with their hearing devices and enjoy a richer quality of life than those who decide not to seek treatment.

Joy Victory has extensive experience editing consumer health information. Her training in particular has focused on how to best communicate evidence-based medical guidelines and clinical trial resultsto the public.She strives to make health content accurate, accessible and engaging to the public. Read more about Joy.

To customize your experience on our site, we collect personal information such as your digital network activity (interactions with our website, IP address) to provide an accurate list of clinics near you. We may also collect personal information such as identifying information (name, email address, phone number), audio recordings of user initiated calls for quality and training purposes, and other forms of personal information. We use this information to provide services you request, such as online hearing test results, downloading information, and/or helping you set an appointment with a participating clinic. Learn more in our Privacy Policy.

screening machines & screeners

Super phosphate (SP), triple super phosphate (TSP) or double super phosphate (DSP) as well as diammonium phosphate (DAP) and monoammonium phosphate (MAP) are mainly used as fertilizers and are subject to strict quality requirements. Since phosphate fertilisers are produced in large quantities of several hundred tonnes per hour, even small efficiency deficits lead to high product losses. The aim of the screening process is to achieve high product purities at maximum throughput - and this can only be achieved by preventing clogging of the screen meshes.

The screening tasks in the processing of nitrogenous fertilizers such as ammonium sulphate (AS), ammonium nitrate (AN), calcium nitrate (CN), potassium nitrate (KN), calcium ammonium nitrate (KAS) and urea range from lump separation to the demanding separation of product fractions as well as dust removal. Screening nitrogen fertilizer with high efficiency and throughput requires precise adjustment of all machine parts as well as a well-functioning self-cleaning system, since urea and co. tend to bind air humidity in the dust fraction and thus clog the screen cloth.

To properly separate sugar requires the application of a high frequency directly to the material. The reason is, that sugar can become sticky even at low humidity levels and also tends to clog the sieve mesh, due to its crystalline grain shape. Screening machines with direct excitation of the screen mesh have therefore proven to be not only energy efficient, but also extremely precise. Thanks to the high accelerations, they reliably separate even finest sugars into several fractions simultaneously.

Efficient separation of metal powdersHigh-alloyed metal powders for 3D printing (additive manufacturing/ rapid technology) should be extremely pure to guarantee a high-quality end product. Dust and agglomerates must therefore be reliably removed from the extremely fine powder during production and recycling. A suitable screening machine should not only be highly precise, but also reduce the loss of valuable product and machine downtime to a minimum.

When processing dry mortar into different fractions, the fluctuating grain size distribution of the crushed limestone, as well as its tendency to clog up the screen mesh, lead to great challenges during screening. Efficient and flexible screening equipment can prevent these negative effects. On the one hand, it must be possible to individually adjust the oscillation amplitudes on each screen deck, and on the other hand, an automatic cleaning system is required to keep the screen surface open and thereby ensure throughput and product quality.

In this particular type of drive, two unbalance motors with different speeds are used. Upstream, a large oscillation amplitude ensures the loosening and removal of the material, while downstream, a small oscillation amplitude at higher acceleration ensures that even difficult to screen products are classified accurately.

Linear and circular vibrating screens are a cost-effective alternative to directly excited screening machines. They can be supplied with several screen decks on request and are available in tailor-made special designs. Their low-maintenance unbalance motors and good accessibility through large inspection openings simplify maintenance tasks.

By overcoming cohesion forces, our high-performance dewatering screens achieve maximum dewatering of solid particles from suspensions with optimized residual moisture content for particles down to less than 1 mm. In wet processing, the precise screening technology ensures efficient disagglomeration of the material and thus optimum separation of coarse and fine material.

Believe it or not for over 70 years it has been our objective to manufacture the best screening machines in the world! For our customers, we always aim to deliver the most effective screening machines for their specific task. Of course, we consider our customers technical and commercial constraints, and adjust each screening machine exactly to their wishes and requirements.

RHEWUM screening machines are Made in Germany or more precisely Made in Remscheid for this reason it is no surprise that we are not the cheapest manufacturer of screening machines, but our sophisticated clientele appreciates our established quality. Still not convinced? We will test your material in our technical center and demonstrate to you the performance of our screening machines, live on site! Clear, committed answers instead of cryptic promises are what you can expect from RHEWUM.

ultrasonic test (ut) basics | welding & ndt

High frequency sound waves (frequency > 20000 HZ) also known as ultrasonic waves are introduced in a test object through a probe, these waves travel through the material on a predictable path. The waves are reflected at interfaces or other interruptions or discontinuity. The reflected waves are detected and then analysed for the possibility of any discontinuity in the test object.

Sound beam is emitted through a probe. The probe is made up of a piezoelectric material. Piezoelectric material has the ability of converting mechanical energy into electrical energy. It is reversible, hence an electrical energy can be converted into mechanical energy or sound energy. The probe receives electric signal from the Ultrasonic machine and converts it to sound beam, these sound beam travels into the test object and gets reflected at interfaces or discontinuity, the piezoelectric material (in probe) converts the reflected sound beam into electrical signal that can be displayed as visual signals on cathode ray tube (CRT) or liquid crystal display (LCD) screen of the machine. Three types of probes are generally used in industries;

In TR probe, two separate crystals are used to transmit and receive the sound energy in the same housing, whereas in Normal and Angle probes same crystal transmits as well as receives the sound beam. The normal probe emits sound energy at right angle to the transducer whereas, the angle probe can emit sound energy at an angle. Three types of angle probes are very popular among the industries, these are

Probe is also called as a search unit or scanning device. The probe is connected with the machine with the help of a connector (connecting wire). The machine has a screen (CRT or LCD) and adjustment/setting keys.

Waves emitted by a normal probe gets reflected at the interfaces or discontinuity (i.e at the change of medium), this is illustrated in figure 3 and figure 4. In figure 3, waves gets reflected at the back surface and the resulting echo is known as a Backwall echo. Whereas, in Figure 4 some of the transmitted waves gets reflected at the flaw, hence two echoes are visible in the machine, one is for the flaw and the other one indicates the backwall.

Figure 5 shows an angle probe, Some part of the transmitted waves gets reflected at the flaw and the resulting echo is visible in the machine. To learn more about angle probe scanning please click here.

Sound waves are propagated, in a material, by the displacement of successive atoms in that material. These sound waves can be propagated in the material in many ways (modes). Three basic modes of propagation of sound energy in metals are being used in Ultrasonic test, these modes are:

Longitudinal waves: Longitudinal waves (Figure 6) are also called as straight or compressional waves. These waveforms are the simplest of all other waveforms. These waveforms exist when the motion of the particle is parallel to the direction of sound beam propagation. These waves have a relatively high velocity and a relatively short wavelength. These waveforms are very useful for detection of inclusions and lamellar-type discontinuities in base metal. Normal probe emits longitudinal waves.

Transverse waves: Transverse waves (Figure 7) are also known as shear waves. These waveforms exist when the motion of particle is perpendicular to the direction of propagation of the sound beam. The velocity of shear waves is approximately half to that of longitudinal waves. The lower velocities provide greater sensitivity to small indications. These waves are more easily dispersed and cannot be propagated in a liquid medium (water). These waves are very useful for the detection of weld discontinuities.

Shear waves are generated by transmitting longitudinal waves into the work piece at a predefined angle. The sensitivity of transverse waves is approximately double than that of longitudinal waves. Angle probe emits longitudinal waves.

Surface waves: Surface waves is the third mode of propagation of sound energy in metal. It is also known as Rayleigh waves. These waves are propagated along the surface of the metal. Since these waves have very little movement below the surface of a metal hence, these waves have a very limited application for the examination of welded joints.

Wave frequency: The sound wave frequency generally used for weld inspection is between 1 MHz to 6 MHz Higher frequency produce sharp and small sound beam which is very useful for thin-walled weldments. A 2.25 MHz frequency is often used in industries.

Couplant: For transmission of ultrasonic waves into the test object, a liquid couplant is generally used. Most commonly used couplants are water, light oil, glycerine, and cellulose gum powder mixed with water. Work piece must be smooth and flat to allow proper coupling of the transducer with the test specimen.

Thanks my friend thanks for your valuable information. Please add more information articles related UT, RT, MPI, and PT. Could you please share how to easily refer to code and standards I meen shortcut methods

Currently you have JavaScript disabled. In order to post comments, please make sure JavaScript and Cookies are enabled, and reload the page. Click here for instructions on how to enable JavaScript in your browser.